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A semi-supervised boosting SVM for predicting hot spots at protein-protein Interfaces

BACKGROUND: Hot spots are residues contributing the most of binding free energy yet accounting for a small portion of a protein interface. Experimental approaches to identify hot spots such as alanine scanning mutagenesis are expensive and time-consuming, while computational methods are emerging as...

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Detalles Bibliográficos
Autores principales:	Xu, Bin, Wei, Xiaoming, Deng, Lei, Guan, Jihong, Zhou, Shuigeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521187/ https://www.ncbi.nlm.nih.gov/pubmed/23282146 http://dx.doi.org/10.1186/1752-0509-6-S2-S6

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