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Two combinatorial optimization problems for SNP discovery using base-specific cleavage and mass spectrometry

BACKGROUND: The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery is based on base-specific cleavage and mass spectrometry. However, it is still v...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Wu, Qiong, Sun, Ruimin, Zhang, Louxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521188/
https://www.ncbi.nlm.nih.gov/pubmed/23282116
http://dx.doi.org/10.1186/1752-0509-6-S2-S5