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Two combinatorial optimization problems for SNP discovery using base-specific cleavage and mass spectrometry
BACKGROUND: The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery is based on base-specific cleavage and mass spectrometry. However, it is still v...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521188/ https://www.ncbi.nlm.nih.gov/pubmed/23282116 http://dx.doi.org/10.1186/1752-0509-6-S2-S5 |