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MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters

BACKGROUND: Functional annotations are available only for a very small fraction of microRNAs (miRNAs) and very few miRNA target genes are experimentally validated. Therefore, functional analysis of miRNA clusters has typically relied on computational target gene prediction followed by Gene Ontology...

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Detalles Bibliográficos
Autores principales: Lee, Su Yeon, Sohn, Kyung-Ah, Kim, Ju Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521213/
https://www.ncbi.nlm.nih.gov/pubmed/23281707
http://dx.doi.org/10.1186/1471-2164-13-S7-S17