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Feasibility of using 454 pyrosequencing for studying quasispecies of the whole dengue viral genome
BACKGROUND: Dengue is the world's most common mosquito-borne viral disease. Poor proofreading by RNA polymerase during its replication results in the accumulation of mutations in its genome. This leads to a diversity of genotypes in the viral population termed quasispecies. Quasispecies play an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521222/ https://www.ncbi.nlm.nih.gov/pubmed/23281804 http://dx.doi.org/10.1186/1471-2164-13-S7-S7 |