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Mechanisms of CFTR Folding at the Endoplasmic Reticulum

In the past decade much has been learned about how Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) folds and misfolds as the etiologic cause of cystic fibrosis (CF). CFTR folding is complex and hierarchical, takes place in multiple cellular compartments and physical environments, and invo...

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Detalles Bibliográficos
Autores principales: Kim, Soo Jung, Skach, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521238/
https://www.ncbi.nlm.nih.gov/pubmed/23248597
http://dx.doi.org/10.3389/fphar.2012.00201