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Effects of long-term oxygen treatment on α-ketoglutarate dehydrogenase activity and oxidative modifications in mitochondria of the guinea pig heart

OBJECTIVE: Oxygen therapy is used for the treatment of various diseases, but prolonged exposure to high concentrations of O(2 )is also associated with formation of free radicals and oxidative damage. METHODS: In the present study we compared α-ketoglutarate dehydrogenase (KGDH) activity and mitochon...

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Detalles Bibliográficos
Autores principales: Kaplan, P, Tatarkova, Z, Engler, I, Calkovska, A, Mokra, D, Drgova, A, Kovalska, M, Lehotsky, J, Dobrota, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521383/
https://www.ncbi.nlm.nih.gov/pubmed/20156740
http://dx.doi.org/10.1186/2047-783X-14-S4-116