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Effects of long-term oxygen treatment on α-ketoglutarate dehydrogenase activity and oxidative modifications in mitochondria of the guinea pig heart
OBJECTIVE: Oxygen therapy is used for the treatment of various diseases, but prolonged exposure to high concentrations of O(2 )is also associated with formation of free radicals and oxidative damage. METHODS: In the present study we compared α-ketoglutarate dehydrogenase (KGDH) activity and mitochon...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521383/ https://www.ncbi.nlm.nih.gov/pubmed/20156740 http://dx.doi.org/10.1186/2047-783X-14-S4-116 |