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iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies
BACKGROUND: Genome-wide association studies (GWAS) do not provide a full account of the heritability of genetic diseases since gene-gene interactions, also known as epistasis are not considered in single locus GWAS. To address this problem, a considerable number of methods have been developed for id...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521387/ https://www.ncbi.nlm.nih.gov/pubmed/23281813 http://dx.doi.org/10.1186/1471-2164-13-S7-S2 |