Space-related pharma-motifs for fast search of protein binding motifs and polypharmacological targets

BACKGROUND: To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Yuan, Lin, Chun-Yu, Lin, Chih-Ta, Hsu, Kai-Cheng, Chang, Li-Zen, Yang, Jinn-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521469/
https://www.ncbi.nlm.nih.gov/pubmed/23281852
http://dx.doi.org/10.1186/1471-2164-13-S7-S21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521469/
https://www.ncbi.nlm.nih.gov/pubmed/23281852
http://dx.doi.org/10.1186/1471-2164-13-S7-S21

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