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Space-related pharma-motifs for fast search of protein binding motifs and polypharmacological targets
BACKGROUND: To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521469/ https://www.ncbi.nlm.nih.gov/pubmed/23281852 http://dx.doi.org/10.1186/1471-2164-13-S7-S21 |