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A linear-time algorithm for reconstructing zero-recombinant haplotype configuration on a pedigree

BACKGROUND: When studying genetic diseases in which genetic variations are passed on to offspring, the ability to distinguish between paternal and maternal alleles is essential. Determining haplotypes from genotype data is called haplotype inference. Most existing computational algorithms for haplot...

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Detalles Bibliográficos
Autores principales: Lai, En-Yu, Wang, Wei-Bung, Jiang, Tao, Wu, Kun-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521470/
https://www.ncbi.nlm.nih.gov/pubmed/23281626
http://dx.doi.org/10.1186/1471-2105-13-S17-S19