Secreted frizzled-related protein 4 expression is positively associated with responsiveness to Cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers

BACKGROUND: Ovarian cancer is one of the most lethal malignancies in women, as it is frequently detected at an advanced stage, and cancers often become refractory to chemotherapy. Evidence suggests that dysregulation of pro-apoptotic genes plays a key role in the onset of chemoresistance. The secret...

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Detalles Bibliográficos
Autores principales: Saran, Uttara, Arfuso, Frank, Zeps, Nikolajs, Dharmarajan, Arunasalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521476/
https://www.ncbi.nlm.nih.gov/pubmed/23039795
http://dx.doi.org/10.1186/1471-2121-13-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521476/
https://www.ncbi.nlm.nih.gov/pubmed/23039795
http://dx.doi.org/10.1186/1471-2121-13-25

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