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The Nuclear Chaperone Nucleophosmin Escorts an Epstein-Barr Virus Nuclear Antigen to Establish Transcriptional Cascades for Latent Infection in Human B Cells

Epstein-Barr Virus (EBV) is an oncogenic γ-herpesvirus that capably establishes both latent and lytic modes of infection in host cells and causes malignant diseases in humans. Nuclear antigen 2 (EBNA2)-mediated transcription of both cellular and viral genes is essential for the establishment and mai...

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Detalles Bibliográficos
Autores principales: Liu, Cheng-Der, Chen, Ya-Lin, Min, Yi-Li, Zhao, Bo, Cheng, Chi-Ping, Kang, Myung-Soo, Chiu, Shu-Jun, Kieff, Elliott, Peng, Chih-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521654/
https://www.ncbi.nlm.nih.gov/pubmed/23271972
http://dx.doi.org/10.1371/journal.ppat.1003084