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Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

Dynamic, mRNA-containing stress granules (SGs) form in the cytoplasm of cells under environmental stresses, including viral infection. Many viruses appear to employ mechanisms to disrupt the formation of SGs on their mRNAs, suggesting that they represent a cellular defense against infection. Here, w...

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Detalles Bibliográficos
Autores principales: Panas, Marc D., Varjak, Margus, Lulla, Aleksei, Er Eng, Kai, Merits, Andres, Karlsson Hedestam, Gunilla B., McInerney, Gerald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521679/
https://www.ncbi.nlm.nih.gov/pubmed/23087212
http://dx.doi.org/10.1091/mbc.E12-08-0619