Cargando…

G9a mediates Sharp-1–dependent inhibition of skeletal muscle differentiation

Sharp-1, a basic helix-loop-helix transcription factor, is a potent repressor of skeletal muscle differentiation and is dysregulated in muscle pathologies. However, the mechanisms by which it inhibits myogenesis are not fully understood. Here we show that G9a, a lysine methyltransferase, is involved...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Belinda Mei Tze, Gopinadhan, Suma, Kok, Wai Kay, Shankar, Shilpa Rani, Gopal, Pooja, Bharathy, Narendra, Wang, Yaju, Taneja, Reshma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521685/
https://www.ncbi.nlm.nih.gov/pubmed/23087213
http://dx.doi.org/10.1091/mbc.E12-04-0311