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Taxol-stabilized microtubules promote the formation of filaments from unmodified full-length Tau in vitro
Tau is a neuronal protein that stabilizes the microtubule (MT) network, but it also forms filaments associated with Alzheimer's disease. Understanding Tau–MT and Tau–Tau interactions would help to establish Tau function in health and disease. For many years, literature reports on Tau–MT binding...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521687/ https://www.ncbi.nlm.nih.gov/pubmed/23087208 http://dx.doi.org/10.1091/mbc.E12-05-0374 |