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Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT–dependent neurite outgrowth in Aplysia bag cell neurons

Neurite outgrowth in response to soluble growth factors often involves changes in intracellular Ca(2+); however, mechanistic roles for Ca(2+) in controlling the underlying dynamic cytoskeletal processes have remained enigmatic. Bag cell neurons exposed to serotonin (5-hydroxytryptamine [5-HT]) respo...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Feng, Hyland, Callen, Van Goor, David, Forscher, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521690/
https://www.ncbi.nlm.nih.gov/pubmed/23097492
http://dx.doi.org/10.1091/mbc.E12-10-0715