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Histone H1 compacts DNA under force and during chromatin assembly

Histone H1 binds to linker DNA between nucleosomes, but the dynamics and biological ramifications of this interaction remain poorly understood. We performed single-molecule experiments using magnetic tweezers to determine the effects of H1 on naked DNA in buffer or during chromatin assembly in Xenop...

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Detalles Bibliográficos
Autores principales: Xiao, Botao, Freedman, Benjamin S., Miller, Kelly E., Heald, Rebecca, Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521692/
https://www.ncbi.nlm.nih.gov/pubmed/23097493
http://dx.doi.org/10.1091/mbc.E12-07-0518