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VipD of Legionella pneumophila Targets Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages

Upon phagocytosis, Legionella pneumophila translocates numerous effector proteins into host cells to perturb cellular metabolism and immunity, ultimately establishing intracellular survival and growth. VipD of L. pneumophila belongs to a family of bacterial effectors that contain the N-terminal lipa...

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Detalles Bibliográficos
Autores principales: Ku, Bonsu, Lee, Kwang-Hoon, Park, Wei Sun, Yang, Chul-Su, Ge, Jianning, Lee, Seong-Gyu, Cha, Sun-Shin, Shao, Feng, Heo, Won Do, Jung, Jae U., Oh, Byung-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521694/
https://www.ncbi.nlm.nih.gov/pubmed/23271971
http://dx.doi.org/10.1371/journal.ppat.1003082