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A Mechanism of Gene Amplification Driven by Small DNA Fragments

DNA amplification is a molecular process that increases the copy number of a chromosomal tract and often causes elevated expression of the amplified gene(s). Although gene amplification is frequently observed in cancer and other degenerative disorders, the molecular mechanisms involved in the proces...

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Detalles Bibliográficos
Autores principales: Mukherjee, Kuntal, Storici, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521702/
https://www.ncbi.nlm.nih.gov/pubmed/23271978
http://dx.doi.org/10.1371/journal.pgen.1003119