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A Mechanism of Gene Amplification Driven by Small DNA Fragments
DNA amplification is a molecular process that increases the copy number of a chromosomal tract and often causes elevated expression of the amplified gene(s). Although gene amplification is frequently observed in cancer and other degenerative disorders, the molecular mechanisms involved in the proces...
Autores principales: | Mukherjee, Kuntal, Storici, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521702/ https://www.ncbi.nlm.nih.gov/pubmed/23271978 http://dx.doi.org/10.1371/journal.pgen.1003119 |
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