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Molecular Evolution of Peptide Ligands with Custom-Tailored Characteristics for Targeting of Glycostructures

As an advanced approach to identify suitable targeting molecules required for various diagnostic and therapeutic interventions, we developed a procedure to devise peptides with customizable features by an iterative computer-assisted optimization strategy. An evolutionary algorithm was utilized to br...

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Detalles Bibliográficos
Autores principales: Röckendorf, Niels, Borschbach, Markus, Frey, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521706/
https://www.ncbi.nlm.nih.gov/pubmed/23271960
http://dx.doi.org/10.1371/journal.pcbi.1002800