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Molecular Evolution of Peptide Ligands with Custom-Tailored Characteristics for Targeting of Glycostructures
As an advanced approach to identify suitable targeting molecules required for various diagnostic and therapeutic interventions, we developed a procedure to devise peptides with customizable features by an iterative computer-assisted optimization strategy. An evolutionary algorithm was utilized to br...
Autores principales: | Röckendorf, Niels, Borschbach, Markus, Frey, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521706/ https://www.ncbi.nlm.nih.gov/pubmed/23271960 http://dx.doi.org/10.1371/journal.pcbi.1002800 |
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