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SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function

The engulfment of apoptotic cells is required for normal metazoan development and tissue remodeling. In Caenorhabditis elegans, two parallel and partially redundant conserved pathways act in cell-corpse engulfment. One pathway, which includes the small GTPase CED-10 Rac and the cytoskeletal regulato...

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Detalles Bibliográficos
Autores principales: Anderson, Courtney, Zhou, Shan, Sawin, Emma, Horvitz, H. Robert, Hurwitz, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521709/
https://www.ncbi.nlm.nih.gov/pubmed/23271977
http://dx.doi.org/10.1371/journal.pgen.1003115