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Covalent α-Synuclein Dimers: Chemico-Physical and Aggregation Properties

The aggregation of α-synuclein into amyloid fibrils constitutes a key step in the onset of Parkinson's disease. Amyloid fibrils of α-synuclein are the major component of Lewy bodies, histological hallmarks of the disease. Little is known about the mechanism of aggregation of α-synuclein. During...

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Detalles Bibliográficos
Autores principales: Pivato, Micaela, De Franceschi, Giorgia, Tosatto, Laura, Frare, Erica, Kumar, Dhruv, Aioanei, Daniel, Brucale, Marco, Tessari, Isabella, Bisaglia, Marco, Samori, Bruno, de Laureto, Patrizia Polverino, Bubacco, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521728/
https://www.ncbi.nlm.nih.gov/pubmed/23272053
http://dx.doi.org/10.1371/journal.pone.0050027