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Morphologic and Gene Expression Criteria for Identifying Human Induced Pluripotent Stem Cells

Induced pluripotent stem (iPS) cells can be generated from somatic cells by the forced expression of four factors, Oct3/4, Sox2, Klf4, and c-Myc. While a great variety of colonies grow during induction, only a few of them develop into iPS cells. Researchers currently use visual observation to identi...

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Detalles Bibliográficos
Autores principales: Wakao, Shohei, Kitada, Masaaki, Kuroda, Yasumasa, Ogura, Fumitaka, Murakami, Toru, Niwa, Akira, Dezawa, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521736/
https://www.ncbi.nlm.nih.gov/pubmed/23272044
http://dx.doi.org/10.1371/journal.pone.0048677