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Morphologic and Gene Expression Criteria for Identifying Human Induced Pluripotent Stem Cells
Induced pluripotent stem (iPS) cells can be generated from somatic cells by the forced expression of four factors, Oct3/4, Sox2, Klf4, and c-Myc. While a great variety of colonies grow during induction, only a few of them develop into iPS cells. Researchers currently use visual observation to identi...
Autores principales: | Wakao, Shohei, Kitada, Masaaki, Kuroda, Yasumasa, Ogura, Fumitaka, Murakami, Toru, Niwa, Akira, Dezawa, Mari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521736/ https://www.ncbi.nlm.nih.gov/pubmed/23272044 http://dx.doi.org/10.1371/journal.pone.0048677 |
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