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Rabbit as a Novel Animal Model for Hepatitis E Virus Infection and Vaccine Evaluation

BACKGROUND: The identification of hepatitis E virus (HEV) from rabbits motivated us to assess the possibility of using rabbits as a non-human primate animal model for HEV infection and vaccine evaluation. METHODOLOGY/PRINCIPAL FINDINGS: First, 75 rabbits were inoculated with seven strains of genotyp...

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Detalles Bibliográficos
Autores principales: Cheng, Xianfeng, Wang, Song, Dai, Xing, Shi, Chengbo, Wen, Yufeng, Zhu, Ming, Zhan, Shenwei, Meng, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521758/
https://www.ncbi.nlm.nih.gov/pubmed/23272124
http://dx.doi.org/10.1371/journal.pone.0051616