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An Early-Age Increase in Vacuolar pH Limits Mitochondrial Function and Lifespan in Yeast
Mitochondria play a central role in ageing. They are considered to be both a target of the ageing process, as well as a contributor to it(1). Alterations in mitochondrial structure and function are evident during ageing in most eukaryotes(2), but how this occurs is poorly understood. Here, we identi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521838/ https://www.ncbi.nlm.nih.gov/pubmed/23172144 http://dx.doi.org/10.1038/nature11654 |