Bypass of a protein roadblock by a replicative DNA helicase

Replicative DNA helicases generally unwind DNA as a single hexamer that encircles and translocates along one strand of the duplex while excluding the complementary strand (“steric exclusion”). In contrast, large T antigen (T-ag), the replicative DNA helicase of the Simian Virus 40 (SV40), is reporte...

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Detalles Bibliográficos
Autores principales: Yardimci, Hasan, Wang, Xindan, Loveland, Anna B., Tappin, Inger, Rudner, David Z., Hurwitz, Jerard, van Oijen, Antoine M., Walter, Johannes C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521859/
https://www.ncbi.nlm.nih.gov/pubmed/23201686
http://dx.doi.org/10.1038/nature11730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521859/
https://www.ncbi.nlm.nih.gov/pubmed/23201686
http://dx.doi.org/10.1038/nature11730

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