The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

Human chromosome ends are capped by shelterin, a protein complex that protects the natural ends from being recognized as sites of DNA damage and also regulates the telomere-replicating enzyme, telomerase(1–3). Shelterin includes the heterodimeric POT1-TPP1 protein, which binds the telomeric single-s...

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Detalles Bibliográficos
Autores principales: Nandakumar, Jayakrishnan, Bell, Caitlin F., Weidenfeld, Ina, Zaug, Arthur J., Leinwand, Leslie A., Cech, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521872/
https://www.ncbi.nlm.nih.gov/pubmed/23103865
http://dx.doi.org/10.1038/nature11648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521872/
https://www.ncbi.nlm.nih.gov/pubmed/23103865
http://dx.doi.org/10.1038/nature11648

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