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Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI

COPI mediates retrograde trafficking from the Golgi to the endoplasmic reticulum (ER) and within the Golgi stack, sorting transmembrane proteins bearing C-terminal KKxx or KxKxx motifs. The structure of KxKxx motifs bound to the N-terminal WD-repeat domain of β'-COP identifies electrostatic con...

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Detalles Bibliográficos
Autores principales: Jackson, Lauren P., Lewis, Michael, Kent, Helen M., Edeling, Melissa A., Evans, Philip R., Duden, Rainer, Owen, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521961/
https://www.ncbi.nlm.nih.gov/pubmed/23177648
http://dx.doi.org/10.1016/j.devcel.2012.10.017