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Influence of a 23S ribosomal RNA mutation in Helicobacter pylori strains on the in vitro synergistic effect of clarithromycin and amoxicillin

BACKGROUND: Clarithromycin (CLR) is the most commonly recommended antibiotic in Helicobacter pylori eradication regimens, but the prevalence of CLR-resistant H. pylori is increasing. CLR resistance is associated with mutations in the 23S rRNA gene. However, H. pylori eradication can still be achieve...

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Detalles Bibliográficos
Autores principales: Sakinc, Türkan, Baars, Barbara, Wüppenhorst, Nicole, Kist, Manfred, Huebner, Johannes, Opferkuch, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522010/
https://www.ncbi.nlm.nih.gov/pubmed/23110798
http://dx.doi.org/10.1186/1756-0500-5-603