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Human DNA Polymerase ϵ Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides

Replicative DNA polymerases (Pols) help to maintain the high fidelity of replication in large part through their strong selectivity against mispaired deoxyribonucleotides. It has recently been demonstrated that several replicative Pols from yeast have surprisingly low selectivity for deoxyribonucleo...

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Detalles Bibliográficos
Autores principales: Göksenin, A. Yasemin, Zahurancik, Walter, LeCompte, Kimberly G., Taggart, David J., Suo, Zucai, Pursell, Zachary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522268/
https://www.ncbi.nlm.nih.gov/pubmed/23093410
http://dx.doi.org/10.1074/jbc.M112.422733