Transcription Factor Positive Regulatory Domain 4 (PRDM4) Recruits Protein Arginine Methyltransferase 5 (PRMT5) to Mediate Histone Arginine Methylation and Control Neural Stem Cell Proliferation and Differentiation

During development of the cerebral cortex, neural stem cells (NSCs) undergo a temporal switch from proliferative (symmetric) to neuron-generating (asymmetric) divisions. We investigated the role of Schwann cell factor 1 (SC1/PRDM4), a member of the PRDM family of transcription factors, in this criti...

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Detalles Bibliográficos
Autores principales: Chittka, Alexandra, Nitarska, Justyna, Grazini, Ursula, Richardson, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522294/
https://www.ncbi.nlm.nih.gov/pubmed/23048031
http://dx.doi.org/10.1074/jbc.M112.392746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522294/
https://www.ncbi.nlm.nih.gov/pubmed/23048031
http://dx.doi.org/10.1074/jbc.M112.392746

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