Cargando…

Evidence for different mechanisms of ‘unhooking’ for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples

BACKGROUND: DNA interstrand cross-links (ICLs) are critical lesions produced by several cancer chemotherapy agents including platinum drugs and nitrogen mustards. We have previously shown in haematological (multiple myeloma) and solid tumours (ovarian cancer) that clinical sensitivity to such agents...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spanswick, Victoria J, Lowe, Helen L, Newton, Claire, Bingham, John P, Bagnobianchi, Alessia, Kiakos, Konstantinos, Craddock, Charles, Ledermann, Jonathan A, Hochhauser, Daniel, Hartley, John A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522549/ https://www.ncbi.nlm.nih.gov/pubmed/23020514 http://dx.doi.org/10.1186/1471-2407-12-436

Ejemplares similares

Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks
por: Bradley, Noah P, et al.
Publicado: (2020)

Increased sensitivity to platinum drugs of cancer cells with acquired resistance to trabectedin
por: Colmegna, B, et al.
Publicado: (2015)

Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy
por: Wynne, P, et al.
Publicado: (2007)

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer
por: Santoro, Valeria, et al.
Publicado: (2015)

A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells
por: Berrada, Sara, et al.
Publicado: (2023)

DNA alkylation and interstrand cross-linking by treosulfan
por: Hartley, J A, et al.
Publicado: (1999)

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
por: Usanova, Svetlana, et al.
Publicado: (2010)

DNA interstrand crosslinking and sequence selectivity of dimethanesulphonates.
por: Ponti, M., et al.
Publicado: (1991)

Mitoxantrone and ametantrone induce interstrand cross-links in DNA of tumour cells
por: Skladanowski, A, et al.
Publicado: (2000)

Hydrated electrons induce the formation of interstrand cross-links in DNA modified by cisplatin adducts
por: Behmand, B, et al.
Publicado: (2020)

Response of two mouse tumours to hyperthermia with CCNU or melphalan.
por: Joiner, M. C., et al.
Publicado: (1982)

DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase.
por: Beith, J., et al.
Publicado: (1997)

Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine.
por: Stratford, I. J., et al.
Publicado: (1988)

Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells
por: Osawa, T, et al.
Publicado: (2011)

Interstrand resistance of SSC magnets
por: Kovachev, V, et al.
Publicado: (1994)

Potentiation of melphalan activity against a murine tumour by nitroimidazole compounds.
por: Sheldon, P. W., et al.
Publicado: (1982)

Melphalan uptake in relation to vascular and extracellular space of human lung-tumour xenografts.
por: Wist, E., et al.
Publicado: (1981)

Enhancement of melphalan-induced tumour cell killing by misonidazole: an interaction of competing mechanisms.
por: Horsman, M. R., et al.
Publicado: (1984)

Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion
por: de Wilt, J H W, et al.
Publicado: (2000)

Chemotherapy with 5-fluorouracil, cisplatin and streptozocin for neuroendocrine tumours
por: Turner, N C, et al.
Publicado: (2010)

Optimal Interstrand Bridges for Collagen-like Biomaterials
por: Tanrikulu, I. Caglar, et al.
Publicado: (2014)

Intravitreal melphalan for persistent retinoblastoma vitreous seeds
por: Redondo-Villanueva, Marie Jeazelle H., et al.
Publicado: (2022)

Influence of anaesthetics on tumour-cell kill and repopulation in B16 melanoma treated with melphalan.
por: Peacock, J. H., et al.
Publicado: (1978)

The effect of misonidazole combined with WR2721 on tumour response and leucopenia due to cyclophosphamide or melphalan.
por: McNally, N. J.
Publicado: (1982)

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis
por: Enoiu, Milica, et al.
Publicado: (2012)

Decreased melphalan accumulation in a human breast cancer cell line selected for resistance to melphalan.
por: Moscow, J. A., et al.
Publicado: (1993)

Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats
por: Wilt, J H W de, et al.
Publicado: (1999)

Monofunctional and Interstrand DNA Adducts of Platinum(II) Complexes
por: Brabec, Viktor, et al.
Publicado: (1994)

Models for interpreting interstrand resistance measurements in Rutherford cables
por: Neal, M, et al.
Publicado: (1994)

Single Molecule Analysis of Laser Localized Interstrand Crosslinks
por: Huang, Jing, et al.
Publicado: (2016)

UHRF1 is a sensor for DNA interstrand crosslinks
por: Liang, Chih-Chao, et al.
Publicado: (2015)

Mechanisms of interstrand DNA crosslink repair and human disorders
por: Hashimoto, Satoru, et al.
Publicado: (2016)

Transcription-Coupled Repair of DNA Interstrand Crosslinks by UVSSA
por: Liebau, Rowyn Church, et al.
Publicado: (2023)

Interstrand Aminoacyl Transfer in a tRNA Acceptor Stem-Overhang Mimic
por: Wu, Long-Fei, et al.
Publicado: (2021)

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment
por: Ip, Laura R. H., et al.
Publicado: (2015)

Modified dose of melphalan-prednisone in multiple myeloma patients receiving bortezomib plus melphalan-prednisone treatment
por: Lee, Se Ryeon, et al.
Publicado: (2019)

Characterization of the Human SNM1A and SNM1B/Apollo DNA Repair Exonucleases
por: Sengerová, Blanka, et al.
Publicado: (2012)

Modulation of Cell Metabolic Pathways and Oxidative Stress Signaling Contribute to Acquired Melphalan Resistance in Multiple Myeloma Cells
por: Zub, Kamila Anna, et al.
Publicado: (2015)

Changes in the response of the RIF-1 tumour to melphalan in vivo induced by inhibitors of nuclear ADP-ribosyl transferase.
por: Horsman, M. R., et al.
Publicado: (1986)

Melphalan sensitivity as a function of progressive metastatic growth in two subpopulations of a mouse mammary tumour.
por: Miller, B. E., et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_pdja1n99imjht0mlgpjirldkpv