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Hepatitis B virus X protein suppresses caveolin-1 expression in hepatocellular carcinoma by regulating DNA methylation

BACKGROUND: To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). METHODS: The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus (HBV)-infected hepatocellular carcinoma (HCC) s...

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Detalles Bibliográficos
Autores principales: Yan, Jun, Lu, Qian, Dong, Jiahong, Li, Xiaowu, Ma, Kuansheng, Cai, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522558/
https://www.ncbi.nlm.nih.gov/pubmed/22894556
http://dx.doi.org/10.1186/1471-2407-12-353