Cargando…

Hepatitis B virus X protein suppresses caveolin-1 expression in hepatocellular carcinoma by regulating DNA methylation

BACKGROUND: To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). METHODS: The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus (HBV)-infected hepatocellular carcinoma (HCC) s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Jun, Lu, Qian, Dong, Jiahong, Li, Xiaowu, Ma, Kuansheng, Cai, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522558/ https://www.ncbi.nlm.nih.gov/pubmed/22894556 http://dx.doi.org/10.1186/1471-2407-12-353

Ejemplares similares

The Biological Function of Hepatitis B Virus X Protein in Hepatocellular Carcinoma
por: Xu, Qiaodong, et al.
Publicado: (2019)

Effect of the pringle maneuver on tumor recurrence of hepatocellular carcinoma after curative resection (EPTRH): a randomized, prospective, controlled multicenter trial
por: Xiaobin, Feng, et al.
Publicado: (2012)

14‐3‐3ζ binds to hepatitis B virus protein X and maintains its protein stability in hepatocellular carcinoma cells
por: Tang, Yufu, et al.
Publicado: (2018)

DNA methylation biomarkers for hepatocellular carcinoma
por: Fan, Guorun, et al.
Publicado: (2018)

Aberrant DNA methylation in hepatocellular carcinoma tumor suppression (Review)
por: DONG, YOUHONG, et al.
Publicado: (2014)

Post-operative pericardial effusion following treatment of small hepatocellular carcinoma with radiofrequency ablation: A case report
por: ZHANG, ZHEBO, et al.
Publicado: (2014)

Inactivation of tumor suppressor TAp63 by hepatitis B virus X protein in hepatocellular carcinoma
por: Xie, Bangxiang, et al.
Publicado: (2022)

DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma
por: Zheng, Yinan, et al.
Publicado: (2019)

lncENST Suppress the Warburg Effect Regulating the Tumor Progress by the Nkx2-5/ErbB2 Axis in Hepatocellular Carcinoma
por: Chen, Geng, et al.
Publicado: (2021)

Missing-in-metastasis B (MIM-B) combined with caveolin-1 promotes metastasis of hepatocellular carcinoma
por: Huang, Xiu-Yan, et al.
Publicado: (2017)

The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hepatocellular Carcinoma
por: Pu, Rui, et al.
Publicado: (2022)

The influence of caveolin-1 gene polymorphisms on hepatitis B virus-related hepatocellular carcinoma susceptibility in Chinese Han population: A case-control study
por: Zhang, Jian, et al.
Publicado: (2017)

Hepatitis B Virus DNA Integration, Chronic Infections and Hepatocellular Carcinoma
por: Bousali, Maria, et al.
Publicado: (2021)

Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma
por: Huang, Danping, et al.
Publicado: (2021)

Hepatitis B virus X protein promotes the growth of hepatocellular carcinoma by modulation of the Notch signaling pathway
por: WANG, FAN, et al.
Publicado: (2012)

Inhibitory effects of resveratrol on hepatitis B virus X protein-induced hepatocellular carcinoma
por: Park, Seungmo, et al.
Publicado: (2017)

Methylation of multiple genes in hepatitis C virus associated hepatocellular carcinoma
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2014)

Hepatitis B Virus DNA Detection by In Situ Hybridization in Human Hepatocellular Carcinoma
por: Lee, Dong Hoo, et al.
Publicado: (1988)

Des-γ-Carboxyprothrombin Plasma Level in Diagnosis of Hepatocellular Carcinoma in a Chinese Population Undergoing Surgery
por: Feng, Xiaobin, et al.
Publicado: (2016)

Up-regulation of brain-expressed X-linked 2 is critical for hepatitis B virus X protein-induced hepatocellular carcinoma development
por: Huang, Fuqiang, et al.
Publicado: (2017)

Methylation Profile of Single Hepatocytes Derived from Hepatitis B Virus-Related Hepatocellular Carcinoma
por: Tao, Ran, et al.
Publicado: (2011)

Hepatitis B Virus and Primary Hepatocellular Carcinoma
por: Sutton, R. N. P.
Publicado: (1982)

Hepatitis B and C Viruses and Hepatocellular Carcinoma
por: Bartosch, Birke
Publicado: (2010)

Hepatitis B Virus-Associated Hepatocellular Carcinoma
por: Rizzo, Giacomo Emanuele Maria, et al.
Publicado: (2022)

Methylation pattern of caveolin-1 in prostate cancer as potential cfDNA biomarker
por: Škara, Lucija, et al.
Publicado: (2023)

Hepatitis B virus whole-X and X protein play distinct roles in HBV-related hepatocellular carcinoma progression
por: Zhang, Yu, et al.
Publicado: (2016)

Radiofrequency ablation versus hepatic resection for the treatment of early-stage hepatocellular carcinoma meeting Milan criteria: a systematic review and meta-analysis
por: Duan, Chenyang, et al.
Publicado: (2013)

Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinomas in Korea.
por: Lee, H. S., et al.
Publicado: (1990)

Hepatitis B Virus X Protein Stimulates Virus Replication Via DNA Methylation of the C-1619 in Covalently Closed Circular DNA
por: Lee, Hyehyeon, et al.
Publicado: (2019)

Postoperative hepatitis B virus reactivation in hepatitis B virus-related hepatocellular carcinoma patients with hepatitis B virus DNA levels <500 copies/mL
por: Xie, Zhi-Bo, et al.
Publicado: (2016)

Case report: Hepatic tuberculosis mimicking hepatocellular carcinoma in a patient with cirrhosis induced by hepatitis B virus
por: Hu, Na, et al.
Publicado: (2022)

Hepatitis B virus X protein disrupts the balance of the expression of circadian rhythm genes in hepatocellular carcinoma
por: YANG, SHENG-LI, et al.
Publicado: (2014)

Prospects of Noncoding RNAs in Hepatocellular Carcinoma
por: Zhou, Huaixiang, et al.
Publicado: (2018)

Hepatitis B virus X protein and hepatitis C virus core protein cooperate to repress E-cadherin expression via DNA methylation
por: Yoon, Hyunyoung, et al.
Publicado: (2022)

Diagnostic Value of the Methylation of Multiple Gene Promoters in Serum in Hepatitis B Virus-Related Hepatocellular Carcinoma
por: Dong, Xueyan, et al.
Publicado: (2017)

Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma
por: Zhan, Hao, et al.
Publicado: (2017)

Association of Hepatitis B Virus Covalently Closed Circular DNA and Human APOBEC3B in Hepatitis B Virus-Related Hepatocellular Carcinoma
por: Luo, Xuan, et al.
Publicado: (2016)

Hypermethylation of GNA14 and its tumor-suppressive role in hepatitis B virus-related hepatocellular carcinoma
por: Song, Guangyuan, et al.
Publicado: (2021)

Long-Term Survival in Patients Receiving Combination Therapy with Resection and Radiofrequency Ablation for Multi-Focal Hepatocellular Carcinoma Classified as Barcelona Clinic Liver Cancer Stage B: A Retrospective Controlled Study
por: Yan, Jun, et al.
Publicado: (2020)

Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B
por: Wang, Xuyang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_c1qte2cboqm3on2fh2diehb461