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Specific Micro RNA-Regulated TetR-KRAB Transcriptional Control of Transgene Expression in Viral Vector-Transduced Cells

Precise control of transgene expression in a tissue-specific and temporally regulated manner is desirable for many basic and applied investigations gene therapy applications. This is important to regulate dose of transgene products and minimize unwanted effects. Previously described methods have emp...

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Detalles Bibliográficos
Autores principales: Pichard, Virginie, Aubert, Dominique, Boni, Sebastien, Battaglia, Severine, Ivacik, Dejana, Nguyen, Tuan Huy, Arbuthnot, Patrick, Ferry, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522580/
https://www.ncbi.nlm.nih.gov/pubmed/23251659
http://dx.doi.org/10.1371/journal.pone.0051952