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Specific Micro RNA-Regulated TetR-KRAB Transcriptional Control of Transgene Expression in Viral Vector-Transduced Cells
Precise control of transgene expression in a tissue-specific and temporally regulated manner is desirable for many basic and applied investigations gene therapy applications. This is important to regulate dose of transgene products and minimize unwanted effects. Previously described methods have emp...
Autores principales: | Pichard, Virginie, Aubert, Dominique, Boni, Sebastien, Battaglia, Severine, Ivacik, Dejana, Nguyen, Tuan Huy, Arbuthnot, Patrick, Ferry, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522580/ https://www.ncbi.nlm.nih.gov/pubmed/23251659 http://dx.doi.org/10.1371/journal.pone.0051952 |
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