Inhibition of N-Terminal Lysines Acetylation and Transcription Factor Assembly by Epirubicin Induced Deranged Cell Homeostasis

Epirubicin (EPI), an anthracycline antitumour antibiotic, is a known intercalating and DNA damaging agent. Here, we study the molecular interaction of EPI with histones and other cellular targets. EPI binding with histone core protein was predicted with spectroscopic and computational techniques. Th...

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Detalles Bibliográficos
Autores principales: Khan, Shahper N., Danishuddin, Mohd, Varshney, Bhavna, Lal, Sunil K., Khan, Asad U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522591/
https://www.ncbi.nlm.nih.gov/pubmed/23251640
http://dx.doi.org/10.1371/journal.pone.0051850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522591/
https://www.ncbi.nlm.nih.gov/pubmed/23251640
http://dx.doi.org/10.1371/journal.pone.0051850

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