Cargando…
C911: A Bench-Level Control for Sequence Specific siRNA Off-Target Effects
Small interfering RNAs (siRNAs) have become a ubiquitous experimental tool for down-regulating mRNAs. Unfortunately, off-target effects are a significant source of false positives in siRNA experiments and an effective control for them has not previously been identified. We introduce two methods of m...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522603/ https://www.ncbi.nlm.nih.gov/pubmed/23251657 http://dx.doi.org/10.1371/journal.pone.0051942 |