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C911: A Bench-Level Control for Sequence Specific siRNA Off-Target Effects

Small interfering RNAs (siRNAs) have become a ubiquitous experimental tool for down-regulating mRNAs. Unfortunately, off-target effects are a significant source of false positives in siRNA experiments and an effective control for them has not previously been identified. We introduce two methods of m...

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Detalles Bibliográficos
Autores principales:	Buehler, Eugen, Chen, Yu-Chi, Martin, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522603/ https://www.ncbi.nlm.nih.gov/pubmed/23251657 http://dx.doi.org/10.1371/journal.pone.0051942

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