TRPM8 Ion Channels Differentially Modulate Proliferation and Cell Cycle Distribution of Normal and Cancer Prostate Cells

Overexpression of the cation-permeable channel TRPM8 in prostate cancers might represent a novel opportunity for their treatment. Inhibitors of TRPM8 reduce the growth of prostate cancer cells. We have used two recently described and highly specific blockers, AMTB and JNJ41876666, and RNAi to determ...

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Detalles Bibliográficos
Autores principales: Valero, María Ll., Mello de Queiroz, Fernanda, Stühmer, Walter, Viana, Félix, Pardo, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522609/
https://www.ncbi.nlm.nih.gov/pubmed/23251635
http://dx.doi.org/10.1371/journal.pone.0051825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522609/
https://www.ncbi.nlm.nih.gov/pubmed/23251635
http://dx.doi.org/10.1371/journal.pone.0051825

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