4F Decreases IRF5 Expression and Activation in Hearts of Tight Skin Mice

The apoAI mimetic 4F was designed to inhibit atherosclerosis by improving HDL. We reported that treating tight skin (Tsk(−/+)) mice, a model of systemic sclerosis (SSc), with 4F decreases inflammation and restores angiogenic potential in Tsk(−/+) hearts. Interferon regulating factor 5 (IRF5) is impo...

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Detalles Bibliográficos
Autores principales: Xu, Hao, Krolikowski, John G., Jones, Deron W., Ge, Zhi-Dong, Pagel, Paul S., Pritchard, Kirkwood A., Weihrauch, Dorothée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522636/
https://www.ncbi.nlm.nih.gov/pubmed/23251680
http://dx.doi.org/10.1371/journal.pone.0052046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522636/
https://www.ncbi.nlm.nih.gov/pubmed/23251680
http://dx.doi.org/10.1371/journal.pone.0052046

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