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Blinded Prospective Evaluation of Computer-Based Mechanistic Schizophrenia Disease Model for Predicting Drug Response

The tremendous advances in understanding the neurobiological circuits involved in schizophrenia have not translated into more effective treatments. An alternative strategy is to use a recently published ‘Quantitative Systems Pharmacology’ computer-based mechanistic disease model of cortical/subcorti...

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Detalles Bibliográficos
Autores principales: Geerts, Hugo, Spiros, Athan, Roberts, Patrick, Twyman, Roy, Alphs, Larry, Grace, Anthony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522663/
https://www.ncbi.nlm.nih.gov/pubmed/23251349
http://dx.doi.org/10.1371/journal.pone.0049732