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Phosphorylation of SET Protein at Ser171 by Protein Kinase D2 Diminishes Its Inhibitory Effect on Protein Phosphatase 2A

We previously reported that protein kinase D2 (PKD2) in T cells is promptly activated after T-cell receptor (TCR) stimulation and involved in the activation of interleukin-2 promoter and T cell death, and that one of its candidate substrate is SET protein, a natural inhibitor for protein phosphatase...

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Detalles Bibliográficos
Autores principales: Irie, Atsushi, Harada, Kumiko, Araki, Norie, Nishimura, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522678/
https://www.ncbi.nlm.nih.gov/pubmed/23251465
http://dx.doi.org/10.1371/journal.pone.0051242