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Low SIRT3 Expression Correlates with Poor Differentiation and Unfavorable Prognosis in Primary Hepatocellular Carcinoma

SIRT3, a mitochondrial sirtuin belonging to nicotinamide adenine nucleotide (NAD) dependent deacetylases, is implicated in metabolism, longevity and carcinogenesis. SIRT3 expression and its significance in hepatocellular carcinoma (HCC) remain largely unclear. In this study, we demonstrated that SIR...

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Detalles Bibliográficos
Autores principales: Zhang, Chris Zhiyi, Liu, Lili, Cai, Muyan, Pan, Yinghua, Fu, Jia, Cao, Yun, Yun, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522714/
https://www.ncbi.nlm.nih.gov/pubmed/23272146
http://dx.doi.org/10.1371/journal.pone.0051703