Cargando…
Hippo Pathway Phylogenetics Predicts Monoubiquitylation of Salvador and Merlin/Nf2
Recently we employed phylogenetics to predict that the cellular interpretation of TGF-β signals is modulated by monoubiquitylation cycles affecting the Smad4 signal transducer/tumor suppressor. This prediction was subsequently validated by experiments in flies, frogs and mammalian cells. Here we app...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522738/ https://www.ncbi.nlm.nih.gov/pubmed/23272121 http://dx.doi.org/10.1371/journal.pone.0051599 |