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Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer

The complexity of gene regulation has created obstacles to defining mechanisms that establish the patterns of gene expression characteristic of the different clinical phenotypes of breast cancer. TFAP2C is a transcription factor, which plays a critical role in the regulation of both estrogen recepto...

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Detalles Bibliográficos
Autores principales: Kulak, Mikhail V., Cyr, Anthony R., Woodfield, George W., Bogachek, Maria, Spanheimer, Philip M., Li, Tiandao, Price, David H., Domann, Frederick E., Weigel, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522755/
https://www.ncbi.nlm.nih.gov/pubmed/22964634
http://dx.doi.org/10.1038/onc.2012.400